
Help Protect Your Pet From Harmful Parasites with One Monthly Application

Revolution provides broad coverage in one simple, monthly topical application.
Protects dogs against fleas, ticks*, ear mites, heartworm disease, and sarcoptic mites.
Protects cats against fleas, ear mites, heartworm disease, roundworms, and hookworms.
Revolution is available from select retailers and vets with a valid prescription.
Revolution does not require gloves to apply or separation time after application.
Simply wash your hands after applying and continue spending time with your pet as usual.
One monthly dose protects pets against common parasites.
Demonstrated safe for dogs at least 6 weeks of age, and for cats at least 8 weeks of age.
It’s important to apply Revolution at the same time every month to keep your pet protected. Stay on track with our monthly text or email reminders.
Parasites are not just “outdoor-only.” Any dog or cat could come in contact with harmful pests at any time of year.
Revolution is demonstrated safe for dogs as young as 6 weeks of age, and cats as young as 8 weeks of age.
Fleas can hitchhike indoors on your cat, other pets or creatures, on shoes and clothes, or get inside through doors and windows.
Tapeworms and fleas tend to go hand in hand. That's because fleas can host tapeworms and then give them to your cat. So when you keep your cat protected from fleas, you help reduce their risk from tapeworms.1
Flea bites can cause intense itching and allergies. This scratching can lead to hair loss and uncomfortable skin irritations.1
Keeping your dog safe from ticks is important. Even if you avoid wooded areas and carefully check your dog after being outside, it's still easy to miss ticks that may have crawled under the fur or in the ears.
They can cause skin irritation and allergic reactions.2,3
These “hitchhikers” can invade your home on other pets and cause severe irritation, including:4
Red, itchy, painful ears.
Dark brown discharge in the ears.
Inflamed ears.
Damage to the ears caused by excessive scratching.
Transmission to other cats and pets through direct contact.
Just 1 bite from an infected mosquito can give your dog or cat heartworms.7 If left untreated, heartworm disease can eventually cause:
Severe lung issues and breathing difficulty.
Damage to other organs, like the liver and kidneys.
Heart failure, in extreme cases.
If left untreated in dogs, these mites cause a skin disease referred to as sarcoptic mange, also know as scabies. Signs of an infection include:
Intense itching, scratching, and biting around the ears and elbows.
Red bumps, reddened or inflamed skin.
Crusty scabs or scales that can spread to larger areas of the skin.
Hair loss.
Roundworms get into your home—and into your cat— through contaminated soil, the dirt on your shoes, or infected prey like rodents or bugs.8,9
Major roundworm infections in cats can cause vomiting, weight loss, hair changes, and a potbellied appearance.8,9
Hookworms can cause anemia, weight loss, and diarrhea in infected cats.10
Severe hookworm infections can be fatal, especially in kittens.10
IMPORTANT SAFETY INFORMATION: See full Prescribing Information. Do not use Revolution on sick, weak, or underweight animals. Use only on cats 8 weeks and older. Use only on dogs 6 weeks and older. Prior to administration, dogs should be tested for heartworms. In cats, side effects may include digestive upset and temporary hair loss at application site with possible inflammation. In people, Revolution may be irritating to skin and eyes. Wash hands after use.
Simparica Trio
Use with caution in dogs with a history of seizures. Simparica Trio contains sarolaner, a member of the isoxazoline class which has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in dogs with or without a history of neurologic disorders. The safe use of Simparica Trio has not been evaluated in breeding, pregnant, or lactating dogs. The most frequently reported adverse reactions in clinical trials were vomiting and diarrhea. See full Prescribing Information.
Revolution Plus
The safe use of Revolution Plus has not been established in kittens less than 8 weeks old or in breeding, pregnant or lactating cats. Reported side effects in clinical trials included lethargy and anorexia. Use with caution in cats with a history of neurologic disorders. Revolution Plus contains sarolaner, a member of the isoxazoline class which has been associated with neurologic adverse reactions, such as tremors, ataxia, and seizures in cats with or without a history of neurologic disorders. In humans, Revolution Plus may be irritating to skin and eyes. See full Prescribing Information.
*The American dog tick (Dermacenter variabilis)
References:
Cat Owners — Fleas. Companion Animal Parasite Council. Available at: http://www.petsandparasites.org/cat-owners/fleas/. Accessed March 24, 2025.
Cat Owners — Ticks. Companion Animal Parasite Council. Available at: http://www.petsandparasites.org/cat-owners/ticks/. Accessed March 24, 2025.
Companion Animal Parasite Council. Ticks. April 12, 2017. https://capcvet.org/guidelines/ticks. Accessed March 24, 2025.
Companion Animal Parasite Council: Otodectic Mite (Ear Mite). Available at https://www.capcvet.org/guidelines/otodectic-mite/. Accessed April 8 2025.
Atkins CE, DeFrancesco TC, Coats JR, Sidley JA, Keene BW. Heartworm infection in cats: 50 cases (1985-1997). J Am Vet Med Assoc. 2000;217(3):355-358.
Cat Owners — Heartworms. Companion Animal Parasite Council. Available at: http://www.petsandparasites.org/cat-owners/heartworms/. Accessed March 24, 2025.
Heartworm in cats. American Heartworm Society. https://www.heartwormsociety.org/heartworms-in-cats. Accessed March 24, 2025.
Gastrointestinal parasites of cats. Cornell University College of Veterinary Medicine. https://www.vet.cornell.edu/departments-centers-and-institutes/cornell-feline-health-center/health-information/feline-health-topics/gastrointestinal-parasites-cats-brochure. Accessed March 24, 2025.
Cat Owners — Roundworms. Companion Animal Parasite Council. http://www.petsandparasites.org/cat-owners/roundworms/. Accessed March 24, 2025.
Cat Owners — Hookworms. Companion Animal Parasite Council. http://www.petsandparasites.org/cat-owners/hookworms/. Accessed March 24, 2025.
ZMR: Feline Most Prescribed Preventative Data 2023.
Stegmann MR, Sherington J, Blanchflower S. Pharmacokinetics and pharmacodynamics of cefovecin in dogs. J Vet Pharmacol Ther. 2006;29(6):501-511.